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☆ Colon cancer rates are rising in young people. If you have two symptoms you should get a colonoscopy, a GI oncologist says.
▼ + stars: | 2024-04-18 | by ( Kim Schewitz | ) www.businessinsider.com time to read: +6 min

Rates of colorectal cancer in people under 50 have been rising by 2% each year since 2011, according to the American Cancer Society. Iron deficiency anemiaIron deficiency anemia, which is where a person has low iron levels, can be a sign of colon cancer. Advertisement"When someone is found to have iron deficiency anemia, I think the important question is always going to be 'why is the person having iron deficiency anemia?' Unintentional weight lossUnintentional weight loss can be a symptom of any type of cancer, including colon cancer, Cleary said. AdvertisementAbdominal painAbdominal pain, aches, or cramps that don't go away could also be an indication that a person has colon cancer.

Persons: Dr, James Cleary, —, it's, Cleary, that's Organizations: Service, American Cancer Society, Centers for Disease Control, CDC, Mayo Clinic, Dana, Farber Cancer Institute, Cancer Locations: Boston

☆ Amazon CEO Andy Jassy says he's committed to cost cutting while investing in AI in shareholder letter
▼ + stars: | 2024-04-11 | by ( Annie Palmer | In Annierpalmer | ) www.cnbc.com time to read: +41 min

This work diminished short-term revenue, but was best for customers, much appreciated, and should bode well for customers and AWS longer-term. We're also making progress on many of our newer business investments that have the potential to be important to customers and Amazon long-term. Being intentional about building primitives requires patience. Customers building their own FM must tackle several challenges in getting a model into production. Customers' AI models contain some of their most sensitive data.

Persons: Andy Jassy, Jassy, Jeff Bezos, he's, we've, Martha Stewart, Clinique, we're, We've, bode, We're, I've, iterating, We'd, we'd, Fox, affordably, you've, They're, Anthropic, that's, Claude, Dana, debugs, Slack Organizations: Amazon, Services, AWS, Deal, Prime, MGM, Savings, Regions, Citadel, Target, Storage Service, Netflix, Disney, Max, Paramount, CIA, . Intelligence, Amazon Freight, Carrier, Amazon Shipping, Foods, Drones, Amazon Pharmacy, Amazon Clinic, Robotics, Nvidia, Ricoh, NatWest, FMs, Meta, Bridgewater Associates, Farber Cancer Institute, Delta Air Lines, Intuit, KT, Lonely, LexisNexis, Netsmart, Pfizer, PGA, Rocket Companies, Siemens, Media, Inc Locations: North America, U.S, Europe, India, Brazil, Australia, Mexico, Middle East, Africa, Malaysia, New Zealand, Kingdom of Saudi Arabia, Thailand, Berlin, Hulu, Amdocs, Genomics England, GoDaddy, GenAI

☆ There’s still no standard test to detect pancreatic cancer early. Scientists are working to change that
▼ + stars: | 2024-04-08 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +11 min

But there is no standard test to detect early cases of pancreatic cancer, before cancer cells have spread and when surgery is more likely to be helpful. But many studies investigating the potential of liquid biopsy tests for the early detection of pancreatic cancer are still in the early phases. The researchers found that their liquid biopsy approach detected 93% of pancreatic cancers among the US volunteers in their study, 91% of pancreatic cancers in the South Korean cohort and 88% of pancreatic cancers in the Chinese cohort. But there is no blood test that can detect early pancreatic cancer. “Smoking is the most important avoidable risk factor for pancreatic cancer,” according to the American Cancer Society.

Persons: ”, Brian Wolpin, ” Wolpin, “ There’s, Ajay Goel, ” Goel, “, Goel, Al Neugut, Columbia University’s Herbert, Dr, Sanjay Gupta, ” Neugut, “ It’s, It’s, Wolpin Organizations: CNN, Dana, Farber Cancer Institute, US Preventive Services Task Force, American Association for Cancer Research, Hope Comprehensive Cancer Center, Molecular Diagnostics, Therapeutics, Surgeons, University of Pennsylvania, UC San Diego, Columbia, Columbia University’s Herbert Irving Comprehensive Cancer Center, Columbia University Mailman School of Public Health, CNN Health, American Cancer Society Locations: United States, City, Japan, South Korea, China, City of Hope, Hope

☆ As the world ages, cancer cases are projected to rise, hitting some countries like ‘a tidal wave’
▼ + stars: | 2024-04-04 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +7 min

Now, a report from the American Cancer Society projects that by 2050, the number of people with cancer could rise 77%. Overall, the top 10 cancer types in both men and women accounted for more than 60% of newly diagnosed cancer cases and cancer deaths, according to the report. Lung cancer was also the leading cause of cancer deaths, followed by colorectal, liver, breast in women, stomach, pancreatic, esophagus, prostate, cervical and leukemia. “While we do see lung cancers that are not related to smoking, the number one cause of lung cancer is smoking. “Interestingly, pollution and other airborne environmental exposures probably increase the risk of lung cancer in many parts of the world.

Persons: ”, William Dahut, ” Dahut, “ We’re, Lung, Ahmedin Jemal, Dr, Bilal Siddiqui, there’s, Harold Burstein, ” Burstein, “, Sanjay Gupta, Burstein Organizations: CNN, American Cancer Society, Cancer, Global Cancer, Health, University of Texas, Anderson Cancer Center, Dana, Farber Cancer Institute, Harvard Medical School, CNN Health Locations: Saharan Africa, South America, Asia, China

☆ Oncologist: Kate’s diagnosis is part of a troubling trend
▼ + stars: | 2024-03-27 | by ( Jalal Baig | ) edition.cnn.com time to read: +7 min

As a medical oncologist, I am heartbroken — but hardly surprised. In fact, it is part of a rising global trend in which newly diagnosed cancer patients are getting younger. The global incidence of early-onset cancer increased by 79.1% and early-onset cancer deaths rose by 27.7% from 1990 to 2019, a 2023 study in the journal BMJ Oncology found. And because early-onset cancers are often diagnosed at advanced stages, they were once thought to be biologically different and more pernicious than their older counterparts. Younger patients may be pregnant at the start of therapy or worry about the effects on fertility.

Persons: Jalal Baig, Catherine , Princess of Wales, Kimmie Ng, “, haven’t, oncologist Jalal Baig, Suneel Kamath, ” Kamath Organizations: Washington Post, NBC News, Foreign, CNN, BMJ Oncology, American Medical Association, Dana, Farber Cancer Institute, Boston Globe, Cleveland Clinic Taussig Cancer Institute, for Young, Cleveland Clinic, US Preventive Services Task Force Locations: Chicago, Washington, United States, Wales

☆ Kate Middleton took time to explain her cancer diagnosis to her kids before announcing it publicly. Here's how to have conversations about cancer with young ones.
▼ + stars: | 2024-03-23 | by ( Erin Snodgrass | ) www.businessinsider.com time to read: +7 min

Use clear languageWhen telling kids about a parent's cancer diagnosis, medical experts said it's important for adults to be as honest as possible in an age-appropriate way. AdvertisementKids three and younger are too little to understand what a cancer diagnosis means. Lastly, teenagers can comprehend the difficult aspects of a cancer diagnosis and will probably start to internalize their feelings, Villena said. AdvertisementUltimately, medical experts said parents should use their best judgment regarding how much information to share with their kids. Be prepared for questionsQuestions are common as kids try to process a parent's cancer diagnosis, experts said.

Persons: —, Kate Middleton, Princess, Wales, Kate, Prince William, Prince George, Princess Charlotte, Prince Louis, Elizabeth Farrell, Dana, Farrell, Dr, Ari Yares, Yares, Jonathan Villena, Villena, Young, it's, they're, we'll, Getty Organizations: Service, Business, CNN, Dana Farber Cancer Institute, BBC, American Cancer Society Locations: Kensington

☆ The woman behind the next big thing in cancer treatment
▼ + stars: | 2024-02-20 | by ( Katie Hunt | ) edition.cnn.com time to read: +12 min

Christine Olsson/AFP/Getty ImagesWu’s research focused on small mutations in cancer tumor cells. However, in many cases, cancer vaccines have failed to live up to their promise — largely because the right target hasn’t been found. “This is a fantastic discovery.”By sequencing DNA from healthy and cancer cells, Wu and her team identified a cancer patient’s unique tumor neoantigens. More work is needed before they are a viable treatment options for many cancer patients. To show that these type of cancer vaccines work, much larger randomized control trials are needed.

Persons: Catherine Wu, Boston’s Dana, “, ”, Wu, Lendahl, Dr Patrick Ott, Sam Ogden, Honjo, James Allison, Tasuku Honjo, James P Allison, Christine Olsson, ” Hans, Gustaf Ljunggren, Matt Stone, “ I’m, ” Wu, ” Lendahl, you’ve, It’s, ” Barbara Brigham, BioNTech, ” CNN’s Brenda Goodman Organizations: CNN, Farber Cancer Institute, Royal Swedish Academy of Sciences, Karolinska, Getty, US Food and Drug Administration, FDA, MediaNews, Boston Herald, Merck, Moderna, ”, Covid Locations: Sweden, BioNTech, Rome

☆ A 34-year-old who worked out regularly and ate healthily noticed blood in his poop. He had stage 3 colon cancer.
▼ + stars: | 2024-02-10 | by ( Kim Schewitz | ) www.businessinsider.com time to read: +6 min

Two days after the colonoscopy, he had just checked into his hotel on a work trip when the doctor called to tell him he had colon cancer . Josh HertingHerting became one of the rising number of young Americans diagnosed with early-onset colon cancer. Herting's dad was diagnosed with stage one colon cancer in his early 50s, but genetic testing showed that this was unrelated to his own diagnosis. He's sharing his story to help raise awareness of the signs and symptoms of colon cancer and to encourage people to be proactive if they notice anything. "As much as you think a colonoscopy isn't fun, colon cancer is a million times worse," he said.

Persons: —, Josh Herting, Herting, doesn't, Martin Luther King Day, Josh Herting Herting, , Kimmie Ng, I'm, you've Organizations: Service, Business, American Cancer, Dana, Farber Cancer Institute, NBC Locations: Massachusetts, American, Boston

☆ Researchers think they have the key to why tardigrades can survive almost anything
▼ + stars: | 2024-02-05 | by ( Jenna Schnuer | ) edition.cnn.com time to read: +6 min

CNN —Tardigrades, also known as water bears, commonly survive in some of Earth’s most challenging environments. Under stress in extreme cold or other harsh environmental conditions, tardigrades’ bodies produce unstable free radicals of oxygen and an unpaired electron, aka a reactive oxygen species that can wreak havoc on the body’s proteins and DNA if they overaccumulate. The survival mechanism kicks off when cysteines, one of the amino acids that forms proteins in the body, come into contact with these oxygen free radicals and becomes oxidized, the researchers found. The free radicals become, so to speak, the hammer used to smash the glass on a fire alarm. “We came up with this idea (that) maybe it’s those species that are actually signaling to the tardigrades to enter their tun state,” she said.

Persons: CNN — Tardigrades, Amanda L, cysteines, ” Smythers, Smythers, Amanda Smythers Smythers, William R, Miller, ” Miller, Jenna Schnuer Organizations: CNN, International Space Station, Dana, Farber Cancer Institute, Harvard Medical School, Getty, University of North, Chapel, Marshall University, Baker University Locations: ”, Boston, Antarctica, University of North Carolina, Huntington , West Virginia, Baldwin City , Kansas, Anchorage , Alaska

☆ More young people are dying of colorectal cancer. Three lifestyle factors could be partly to blame, scientists say.
▼ + stars: | 2024-02-02 | by ( Kim Schewitz | ) www.businessinsider.com time to read: +5 min

Colorectal cancer deaths among younger people in Europe are forecast to rise by around a third in 2024.to rise by around a third in 2024. Obesity, low levels of physical activity, and alcohol might be partly to blame, scientists say. Cancer researchers from the University of Milan, Italy, predicted that colorectal cancer deaths among people aged 25 to 49 will rise significantly in the EU and the UK this year compared to 2018. AdvertisementAlthough they estimated that deaths from colorectal cancer will fall overall in 2024, this is the first year they have predicted a rise in colorectal cancer deaths among younger people. More people drinking alcohol, which has been linked to early-onset colorectal cancer, and less physical activity could also be factors, the study said.

Persons: —, Christina Annunziata, Chadwick Boseman's, Annunziata, Carlo La Vecchia, La Vecchia, Kimmie Ng Organizations: EU, Service, Cancer, University of Milan, American Cancer Society, Oncology, World Health Organization, Dana, Farber Cancer Institute, NBC Locations: Europe, Italy, Germany, Spain, Poland, France, Boston

Allegations of research fakery at a leading cancer center have turned a spotlight on scientific integrity and the amateur sleuths uncovering image manipulation in published research. The blogger, 32-year-old Sholto David, of Pontypridd, Wales, is a scientist-sleuth who detects cut-and-paste image manipulation in published scientific papers. By Jan. 22, the institution said it was in the process of requesting six retractions of published research and that another 31 papers warranted corrections. The sleuths download scientific papers and use software tools to help find problems. Some journals told the AP they are aware of the concerns raised by David's blog post and were looking into the matter.

Persons: Jan, David, He's, Farber, DANA, FARBER, Sholto David, Dana, Laurie Glimcher, William Hahn, sleuths, Claudine Gay, Barrett Rollins, Elisabeth Bik, ” Bik, Ivan Oransky, Oransky, “, ” Oransky, —, ” They're, Bik Organizations: Dana, Farber Cancer Institute, Harvard Medical School, The Harvard Crimson, WHO, Associated Press, American Society for Microbiology, Technology, New York University, “, AP, Associated Press Health, Science Department, Howard Hughes Medical Institute’s Science, Educational Media Group Locations: British, Pontypridd, Wales, PubPeer, California

☆ Colorectal cancer is killing more younger people than ever. 3 people under 50 diagnosed with it shared their first symptoms.
▼ + stars: | 2024-01-23 | by ( Kim Schewitz | ) www.businessinsider.com time to read: +7 min

People under 50 in the US are dying from colorectal cancer at an increasing rate. AdvertisementMore people under the age of 50 are dying of colorectal cancer than ever before, according to the American Cancer Association. The disease is sometimes called colon cancer or rectal cancer, depending on where it starts. When colorectal cancer is caught early, before it has spread, the chance a person will live for another five years is about 90%. AdvertisementShe now visits her gastroenterologist regularly, eats healthy, exercises, and raises awareness of the signs of colorectal cancer.

Persons: —, Kimmie Ng, you've, JJ Singleton, Singleton, Lynch, Tom McKenna, Paula Chambers Raney, Doctors, gastroenterologist, Kim Schewitz, kschewitz@businessinsider.com Organizations: Service, American Cancer Association, Dana, Farber Cancer Institute, NBC Locations: Boston

☆ Harvard cancer institute moves to retract six studies, correct 31 others amid data manipulation claims
▼ + stars: | 2024-01-22 | by ( Matt Egan | ) edition.cnn.com time to read: +2 min

CNN —The Dana-Farber Cancer Institute, a prestigious Harvard teaching school, is moving to retract six studies and correct 31 others following allegations of data manipulation. The steps by the Harvard Medical School affiliate come after a molecular biologist published a blog post earlier this month alleging researchers falsified data by manipulating images. More than 50 papers are part of the ongoing review by Dana-Farber into four researchers, all of whom have faculty appointments at Harvard Medical School. Earlier this month, Sholto David published a blog post titled “Dana-Farberications at Harvard University,” alleging researchers at the cancer institute manipulated images and data. According to Rollins, Dana-Farber said it was already reviewing “potential data errors” in multiple cases that the blog listed and stressed that the issues uncovered do not necessarily amount to misconduct.

Persons: Dana, Farber, Laurie Glimcher, ” Barrett Rollins, “ Dana, Rollins, Claudine Gay, Gay, ”, Sholto David, Farberications, David, ” Rollins Organizations: CNN, Farber Cancer Institute, Harvard, Harvard Medical School, Dana, Ivy League, ” Harvard, Harvard University, Photoshop

☆ Bladder cancer studies suggest new ways to treat the disease and improve survival
▼ + stars: | 2023-10-22 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +9 min

This is one of several new studies exploring ways to improve how bladder cancer is treated. “Ever since I was in med school, a metastatic bladder cancer treatment was gemcitabine and platinum. Urothelial cancer is a type of bladder cancer that begins in the urothelial cells, which line the inside of the bladder. The drug became the first therapy targeting a genetic alteration to be approved by the FDA to treat patients with the most common type of bladder cancer, metastatic urothelial cancer. “These results support nivolumab plus cisplatin-based chemo as a new standard approach for the treatment of metastatic urothelial cancer.”

Persons: vedotin, hadn’t, ”, Thomas Powles, ” Powles, we’ve, —, Powles, Toni Choueiri, Dana, “, enfortumab, ” Choueiri, drugmaker Janssen, Dr, Sanjay Gupta, nivolumab, Matthew Galsky Organizations: CNN, Society for Medical Oncology, University of London, Barts Cancer, US, Inc, Astellas Pharma, Merck, Co, Food and Drug Administration, FDA, EMA, Lank, Genitourinary Oncology, Farber Cancer Institute, ESMO, New England, of Medicine, University of Texas, Anderson Cancer Center, US Food and Drug Administration, National Library of Medicine, CNN Health, Bristol Myers Squibb, Ono Pharmaceutical Company, Cancer, The Tisch Cancer Institute Locations: Madrid, United Kingdom, United States, Europe, Mount Sinai

☆ Rectal Cancer Patients Could Be Spared the Brutal Effects of Radiation
▼ + stars: | 2023-06-04 | by ( Gina Kolata | ) www.nytimes.com time to read: +1 min

That was why researchers took another look at the standard treatment for rectal cancer. But the radiation puts women into immediate menopause and damages sexual function in men and women. Yet radiation treatment, the study found, did not improve outcomes. For colon and rectal cancer specialists, the results can transform their patients’ lives, said Dr. Kimmie Ng, a co-director of the colon and rectal cancer center at the Dana-Farber Cancer Institute, who was not an author of the study. “Now, especially, with patients skewing younger and younger, do they actually need radiation?” she asked.

Persons: Kimmie Ng, Dana, Dr, John Plastaras Organizations: Farber Cancer Institute, Penn Medicine Abramson Cancer Center

☆ Drug cuts risk of breast cancer recurrence for some early-stage patients, trial shows
▼ + stars: | 2023-06-02 | by ( Jen Christensen | ) edition.cnn.com time to read: +6 min

CNN —A drug used in people in the early stage of the most common kind of breast cancer – HR+/HER2- breast cancer – significantly reduced the risk of the cancer returning after treatment, according to a new study. HR+/HER2- breast cancer has tested positive for progesterone and estrogen receptors and negative for HER2. Endocrine therapy generally works well, but for patients with HR+ or HER- breast cancer, there’s still a 10% to 40% chance that the cancer will come back, some studies show. The new trial found that when Kisqali is added to endocrine therapy, it reduces the risk of recurrence by 25% across a broad population of patients with early breast cancer. About 90% of patients who have breast cancer are diagnosed in the early stages.

Persons: there’s, Kisqali, ”, Dennis J, Slamon, Sara Tolaney, ” Tolaney, Anupama Goel, Goel, Dr, Sanjay Gupta, Alberto Montero, ” Montero, Montero Organizations: CNN, US Food and Drug Administration, American Society of Clinical Oncology, Novartis, UCLA, Comprehensive Cancer Center, Oncology, Dana, Farber Cancer Institute, Mount Sinai Tisch Cancer Center, CNN Health, UH Seidman Cancer Center, Case Western Reserve University School of Medicine Locations: Chicago, Ohio, –

☆ China is using AI to raise the dead, and give people one last chance to say goodbye
▼ + stars: | 2023-05-20 | by ( Matthew Loh | ) www.businessinsider.com time to read: +13 min

I would have liked to watch a few more episodes," the grandfather bot replied. Yu told Tang his grandmother needed the chatbot to process her emotions and mourn. As for himself, he declined to share his intimate conversations with his grandfather bot. Like Yu's grandfather bot, Wu's bot produced limited responses. "These emotions might have overwhelmed me too much to work and live my life," he told Tang.

CNN —President Joe Biden will nominate Dr. Monica Bertagnolli, who currently leads the National Cancer Institute, to be the next director of the National Institutes of Health, the White House announced on Monday. Biden called Bertagnolli “a world-class physician-scientist whose vision and leadership will ensure NIH continues to be an engine of innovation to improve the health of the American people,” in a statement Monday. She would lead the country’s medical research agency, overseeing 27 research institutes and centers focused on different areas of medical research, such as cancer, the human genome, as well as allergy and infectious diseases. The nomination to lead NIH marks a fast ascent within the Biden administration for Bertagnolli. In this August 2022 photo, Monica Bertagnolli, newly appointed director of the National Cancer Institute, stands for recognition during remarks by President Joe Biden.

☆ New study suggests Black women should be screened earlier for breast cancer
▼ + stars: | 2023-04-19 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +12 min

CNN —A new study on breast cancer deaths raises questions around whether Black women should screen at earlier ages. Even though Black women have a 4% lower incidence rate of breast cancer than White women, they have a 40% higher breast cancer death rate. “When the breast cancer mortality rate for Black women in their 40s is 27 deaths per 100,000 person-years, this means 27 out of every 100,000 Black women aged 40-49 in the US die of breast cancer during one year of follow-up. They also wrote that health policy makers should pursue equity, not just equality, when it comes to breast cancer screening as a tool to help reduce breast cancer death rates. Having dense tissue in the breast can make it more difficult for radiologists to identify breast cancer on a mammogram, and women with dense breast tissue have a higher risk of breast cancer.

☆ Psychedelic therapies are on the horizon. Who will administer them?
▼ + stars: | 2022-12-26 | by ( Danica Jefferies | Danica Jefferies Is An Intern With The Data Graphics Team For Nbc News Digital. | ) www.nbcnews.com time to read: +11 min

Psychedelic therapy is nowhere near as simple as filling a prescription and taking a pill at home. A clinical psychologist, she founded and now leads the first accredited psychedelic therapy training program in the U.S. at the California Institute of Integral Studies. The psychedelic therapy program entails 150 hours of instruction and several in-person training sessions. So why the growing interest in using psychedelic drugs for mental health? Treatment with psychedelic drugs is not as simple as giving the patient a pill to take at home, and it’s not for everybody.

The first-of-its-kind study was presented Thursday at the San Antonio Breast Cancer Symposium, an annual meeting of breast cancer specialists. Faced with this possibility, Partridge said, many women stop or never start endocrine therapy, against the advice of their doctors. The findings were highly anticipated by other breast cancer specialists. Women in her practice were already making the executive decision to stop endocrine therapy for the chance of having a baby. Johnson was diagnosed with stage 2 breast cancer at age 34.

☆ Targeted therapy shows benefit for people with advanced breast cancer in late-stage trial
▼ + stars: | 2022-12-08 | by ( Jen Christensen | ) edition.cnn.com time to read: +3 min

The details of the trial were presented Thursday at the San Antonio Breast Cancer Symposium. The trial involved 708 adults with HR-positive, HER2-low or -negative breast cancer whose disease has recurred or progressed during or after certain previous treatments. About three-quarters of women with metastatic breast cancer have HR-positive breast cancer. He points to the cancer drug Avastin, which was initially touted as having an advantage in progression-free survival for metastatic breast cancer. Burstein said he is encouraged by many of the presentations at the San Antonio Breast Cancer Symposium.

☆ Colonoscopies may not be as effective as thought, study suggests. Doctors disagree.
▼ + stars: | 2022-10-11 | by ( Https | Media-Cldnry.S-Nbcnews.Com Image Upload Newscms Berkeley-Lovelace-Jr.Jpg | Berkeley Lovelace Jr. | ) www.nbcnews.com time to read: +7 min

What did the colonoscopy study find? With longer monitoring, the results could show a larger reduction of colon cancer risk, said Brawley of Johns Hopkins. Cancer experts reached Monday said their recommendation for colorectal cancer screening remains the same: Regular colonoscopies are key to preventing colon cancer and finding it early. In the U.S., “we have exaggerated the benefits of colon cancer screening,” Brawley said. “We have good studies that show that colon cancer screening is effective.

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